Two sample MR report
ANXA5_Conventional Dendritic Cell against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | -0.1254826 | 0.1827238 | 0.5415711 |
| Weighted median | 5 | -0.0782607 | 0.0286106 | 0.0062309 |
| Inverse variance weighted | 5 | -0.0754834 | 0.0232142 | 0.0011475 |
| Simple mode | 5 | -0.0843195 | 0.0363694 | 0.0812774 |
| Weighted mode | 5 | -0.0814071 | 0.0374487 | 0.0954003 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.4811266 | 3 | 0.9230178 |
| Inverse variance weighted | 0.5572298 | 4 | 0.9676958 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0235162 | 0.0852444 | 0.8005611 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001725 | 0 | TRUE | 0.2127163 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
